Valtrex / Acyclovir is considered safe to use while pregnant
Posted on Wednesday, September 12th, 2007 at 5:53 AMValtrex is actually a very well studied drug. It is a prodrug for acyclovir, which has been around for 30+ years. Valtrex turns into acyclovir after it is absorbed which allows your body to get more of the drug into your system for longer (which is why you take Valtrex less frequently than acyclovir).
Although it has not been officially tested for use during pregnancy (very few drugs ever are as to do this would require testing on pregnant women … not a thing most people are happy with), it is considered safe to use when pregnant — a category “B” medication. There was at one time a pregnancy registry for acyclovir (the drug your body converts Valtrex into) that followed pregnant women. Somewhere close to 1000 women taking Valtrex while pregnant were followed and the rate of defects amongst that group was considered to be the same as for women not taking any medication. There was for a while a registry for Valtrex as well, but it ran for a shorter period of time and, although the results were similar, the number of women followed was not enough to draw as strong of conclusions.
Taking Acyclovir or Valtrex suppressively during the last weeks of pregnancy is recommended. Even though you are passing the antibodies onto your infant, the suppressive therapy should prevent you from shedding the virus and/or having an outbreak. During the last weeks of pregnancy your child is less likely to suffer any ill effects from any medication you may take. This is not to say you should not weigh your options and make your own decisions.
I took Valtrex throughout my pregnancy and my child is fine and beautiful. I was comfortable enough with the drug’s profile that I told my doctor up front that I intended to take the drug throughout my pregnancy to protect my partner.
I doubt you need to be concerned about allergic reactions, especially if you’ve taken the drug before as you would have had the reaction then. Valtrex/Acyclovir have very low allergic profiles (aka even people with a bad history of allergies normally don’t react to them). Antivirals are completely different beasts from antibiotics and just don’t wreak the havoc on your body that an antibiotic can. Valtrex/Acyclovir very specifically targets herpes by mimicking a substance the virus needs to reproduce. When the virus grabs onto the antiviral, the antiviral gets in the way of the virus being able to reproduce. The substance Valtrex/acyclovir mimics is not a substance your body needs so your body doesn’t tend to react to the drug much.
I’m trying to break down a complex bit of biochemistry here, so I may be guilty of oversimplifying how Valtrex/acyclovir works. There are some resources on the net that go into this stuff in detail and you may want to read up on them if you are interested in a more advanced explanation. – Lorraine
If you have something to say about herpes and what it’s like to be pregnant when you have herpes I’d love to hear from you. You can send me bits of advice OR your own personal story and I would be more than happy to publish it so that we can work to help people that don’t know enough about this to make a decision for themselves.
As with anything health related please see your own doctor. Our personal experiences shared do not indicate truth for everybody that is in similar situations. The information shared is based on our own personal experiences. No two herpes cases are alike.
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To Still Worried:
I posted in May 2009, read my post above… I had a healthy 10 pound baby girl in December 2010….No problems whatsoever….. I only took valtrex when I felt a breakout coming on or had a break out… I had just one breakout, and I took valtrex for 3 days, twice a day… And other times, if I felt a breakout coming on, tingling, etc, I immediately took a valtrex with warm water (works instantly), and I was able to keep herpes at bay by just taking that one pill…To me it’s best to look for signs of a potential breakout then take valtres immediately to block it… but if you have real bad breakouts all the time, it’s best to go on suppressive therapy… It’s perfectly safe….Perfectly safe – DONT WORRY
do people take suppressive therapy for life? Is acyclovir also ok for use ALL through pregnancy if valtrex is since its essentially the same drug broken down?
No, people don’t have to stay on suppressive therapy at all. I think folks sometimes assume that you have to always be on antivirals and that’s just not true at all. People have different reasons for using the antivirals and the length of time a person is on them just depends on their situation and why they are taking them. When I was pregnant with my girls I chose to go on suppressive therapy the last 6 weeks of both pregnancy just as a precaution. I wanted to prevent viral activity and/or outbreaks from popping up around the time of delivery.
Yes, it was the same for me. In 2000 I went through a lot of stress which seemed to bring on outbreaks almost weekly and I made the decision to take Famvir for one year (at the time they were marketing it as a cure..) and it really helped. I did not have an outbreak for the entire year and hardly any for years after.
Then like Angela, I took Valtrex for the final weeks of my pregnancies. BIG ANNOUNCEMENT: I am pregnant again and will take it again at the end. And yes, for all those that are counting, that is three babies conceived the old fashioned way (you know, the FUN way), with a husband that continues to test negative for the virus.
Take care all,
Nanci
Congratulations Nanci!! I needed a pick-me-up story today. This will get me out of bed. Thanks. :)
Congratulations Nanci! What wonderful news to be expecting another miracle from God. I’m so happy for you! :)